Agenda

Marché aux puces de Ste Musse

Anonyme — Thu, 03 Dec 2020 17:10:20 +0000

Marché aux puces de Ste Musse Anonyme (non vérifié) jeu 03/12/2020 - 18:10

Emplacement 13 €. Pas de réservation.
Terrain à côté de l'Intermarché (ouvert le dimanche), à proximité de l'hôpital Ste Musse. Nombreuses places de parkings gratuites pour les visiteurs.

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Marché aux puces de Ste Musse

Lieux de l’agenda 04 94 00 00 01 Courriel 04 94 00 00 01 http://example.com Fonction 1 Fonction 2 Fonction 3 Lundi : 15h-18h / Mardi : 9h30-12h30 / Jeudi : 9h30-12h30 / 14h30-18h30

28 rue de la Clé d'Or
00000 Ville
France

43.125892535429, 5.9288730665852 Voges Syndicat Départemental d'électricité Courriel 04 94 00 00 01 On

2020-01-01T05:00:00 2020-01-01T13:00:00

En ce moment un exemple de titre

Anonyme — Thu, 03 Dec 2020 20:19:19 +0000

En ce moment un exemple de titre Anonyme (non vérifié) jeu 03/12/2020 - 21:19

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Concours de pétanque

Anonyme — Thu, 03 Dec 2020 16:54:01 +0000

Concours de pétanque Anonyme (non vérifié) jeu 03/12/2020 - 17:54 Du samedi 7 au dimanche 8 novembre de 9h à 19h. PhD programs

Boulodrome des Lices et Stade Casa d'Italia

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Avenue des Lices
83000 Toulon
France

43.1263907, 5.9367463 Nom Prénom Courriel 08 94 39 25 21 On

2020-11-08T09:00:00 2022-10-09T19:00:00

En ce moment un exemple de titre 2

Anonyme — Thu, 03 Dec 2020 17:05:08 +0000

En ce moment un exemple de titre 2 Anonyme (non vérifié) jeu 03/12/2020 - 18:05

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Téléphérique du mont faron

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Lieux de l’agenda 04 94 00 00 01 Courriel 09 87 65 43 21 http://example.com Labore eiusmod pariatur amet aliquip duis laborum qui tempor exercitation. Lundi : 15h-18h / Mardi : 9h30-12h30 / Jeudi : 9h30-12h30 / 14h30-18h30

2 Boulevard Amiral Vence
83200 Toulon
France

43.1376739, 5.9278507 Nom Prénom Courriel 04 94 00 18 26 On

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2020-11-09T10:30:00 2025-02-05T23:00:00

En ce moment un exemple de titre 3

Anonyme — Thu, 03 Dec 2020 17:06:49 +0000

En ce moment un exemple de titre 3 Anonyme (non vérifié) jeu 03/12/2020 - 18:06

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Phasellus tempus tincidunt massa, at malesuada arcu bibendum id. Appel à projet, PhD programs

Téléphérique du mont faron

2 Boulevard Amiral Vence
83200 Toulon
France

43.1376739, 5.9278507 Nom Prénom Courriel 04 94 00 18 26 On

2020-12-24T14:00:00 2025-05-12T20:00:00

Seminar: Garcia Fernandez - October 12, 2021 11h

sylvie.kemenovic@ens-paris-saclay.fr — Wed, 22 Sep 2021 08:49:06 +0000

Seminar: Garcia Fernandez - October 12, 2021 11h sylvie.kemenov… mer 22/09/2021 - 10:49

Cyclodextrins (cyclomatooligosaccharides, CDs), can be considered as cyclic pieces of the maltodextrin chains of starch. They are composed of glucose monomers with linkages that feature a troncoconic torus with a hydrophobic inner space and a hydrophilic exterior. This unique type of amphiphilicity make CDs capable of including a variety of guests in the cavity and improve their solubility (and often their stability) in biological media, which has been largely exploited in the pharmaceutical industry. Most interestingly, CDs can be chemically modified to build nanosized multifunctional systems with (hierarchical) self-assembling, biological recognition and/or stimuli responsive properties.

The incorporation of CDs in linear and star-type polymers and dendrimers has been realized. Through precision macromolecular synthetic methods, full homogeneity can be preserve, thereby accessing monodisperse molecular nanoparticle-type entities. The strategy can be extended to de novo synthesized (cyclo)oligosaccharides, further expanding the palette of customizable supramolecularly-competent platforms. The amalgamation of diastereomeric purity and multifunctionality (as natural proteins do) is particularly appealing in the biomedical feel. Examples of oligosaccharide-based systems with programmed drug/gene delivery properties will be presented [1-6].

References

[1] J. L. Jiménez Blanco et al., J. Drug Deliv. Sci. Technol. 2017, 42, 18-37.
[2] L. Gallego-Yerga et al., Chem. Eur. J. 2018, 24, 3825-3835.
[3] T. Neva et al., Chem. Eur. J. 2020, 26, 15259-15269.
[4] A. I. Carbajo-Gordillo et al., Biomacromolecules 2020, 21, 5173-5188.
[5] L. Gallego-Yerga et al., Carbohydr. Polym. 2021, 252, 117135.
[6] A. I. Carbajo-Gordillo et al., Chem. Eur. J. 2021, 27, 9429-9438.

Biographical sketch José M. García Fernández

Jose Manuel García Fernández is Research Professor at Institute for Chemical Research, a mixed centre of the Spanish National Research Council (CSIC) and the University of Seville, were he served as Director since 2009 to 2017. During 2018 he assumed the National Coordination of the Chemistry and Chemical Technology Area of the CSIC. He has co-authored over 250 scientific articles, is co-inventor of 19 patents and has supervised 22 PhD Thesis. Current targets of the laboratory include the design of self-assembled glycocarriers for drug and gene delivery, the development of glycodrugs targeting defective glycoconjugate processing enzymes for the treatment of metabolic and age-related diseases and the implementation of new technologies for the preparation of prebiotic oligosaccharides as functional food ingredients.

José M. García Fernández, Institute for Chemical Research, at the University of Sevilla gives a seminar entitled "Oligosaccharide-based nucleic acid delivery: precision chemistry for precision medicine" on October 12, 2021 11am at institut d'alembert (IDA, ENS Paris-Saclay).

Boulodrome des Lices et Stade Casa d'Italia

Avenue des Lices
83000 Toulon
France

43.1263907, 5.9367463 Nom Prénom Courriel 08 94 39 25 21 On

2021-10-12T11:00:00 2021-10-13T13:00:00

En ce moment un exemple de titre 4

Anonyme — Thu, 03 Dec 2020 17:07:55 +0000

En ce moment un exemple de titre 4 Anonyme (non vérifié) jeu 03/12/2020 - 18:07

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Aute amet anim aute nulla. In fugiat elit qui ut incididunt amet exercitation voluptate.

Téléphérique du mont faron

2 Boulevard Amiral Vence
83200 Toulon
France

43.1376739, 5.9278507 Nom Prénom Courriel 04 94 00 18 26 On

2021-12-10T15:00:00